Peyronie's disease

Featured Natural Products for Men's Health Total Balance Men's Plus is an overall complex of pure, natural ingredients that will help to improve your overall health and longevity - your brain function and development, digestive health, energy levels, cellular strength and essential organ function. This natural product addresses the specific needs of the male reproductive system, helping to boost virility and contribute to the prevention of male-specific diseases and conditions. Men's Plus provides a broad spectrum of around 80 of the nutrients that your body needs¡­including vitamins, minerals, trace elements, antioxidants, amino acids, neuronutrients, bioflavonoids, carotenoids, herbal extracts, enzymes and other complementary co-factor ingredients.

The cause of Peyronie's disease is unclear. Many researchers believe the plaque of Peyronie's disease can develop following trauma (hitting or bending) that causes localized bleeding inside the penis. Other cases, which develop over time, may be genetically linked or inherited (passed on from parents to children through genes). In addition, a number of medications list Peyronie's disease as a possible side effect. Most are a type of drug called beta-blockers that are often prescribed for people with heart conditions or high blood pressure. Other drugs that may cause Peyronie's disease are interferon, which is used to treat multiple sclerosis, and Dilantin, an anti-seizure medicine. However, the chance of developing Peyronie's disease from any of these medicines is very low and there is no evidence that Peyronie's disease is related to taking these drugs.

Cases of Peyronie’s that develop over time may be caused by an inherited abnormality of human leukocyte antigen B7 (HLA-B7), suggesting a genetic link. Also, Peyronie’s occurs more frequently in men with family members who have the condition or a connective tissue disorder (e.g., systemic lupus erythematosus). About 30% of patients with Peyronie’s disease also develop hardened tissue in other parts of the body, such as the hand (e.g., Dupuytren’s contracture) or the foot. Microscopic examination of hardened tissue in cases of Peyronie’s disease is consistent with cases of severe inflammation of blood vessels (vasculitis), suggesting the condition may have a vascular (i.e., pertaining to blood vessels) cause. Diabetes, which often leads to blood vessel disease, is also considered a risk factor. The use of the antihypertension medication proprano's disease has also been associated with vitamin E deficiency.

Peyronie's disease can be mild, moderate or severe. It may appear suddenly, or progress slowly over a matter of weeks or months. The progression of symptoms may include:

In many men Peyronie's disease is mild and resolves within a year or two so treatment may be unnecessary. In more severe cases, the hardened lump and deformity persist and may get worse.

Medical therapy with various agents may relieve the discomfort e.g. Vitamin E, intralesional steroids or ultrasonic therapy but these seldom help long-term. Intralesional collagenase is sometimes helpful. Surgery is probably the best treatment but is usually only done after waiting for 1-2 years to allow the plaque to stabilise or disappear. There is less chance of recurrence post surgery if the inflammatory phase of Peyronie's disease has settled and the degree of bending has reached its peak. A semi-rigid prosthesis may be inserted.