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All about impotence (erectile dysfunction) mechanism of erection causes of erectile dysfunction physical causes of impotence psychological causes of impotence impotence or erectile dysfunction treatment non-prescription remedy for impotence MUSE (Medicated Urethral Suppository for Erection) Viagra (sildenafil citrate) Levitra (vardenafil) Cialis (tadalafil) penile injection therapy for erectile dysfunction penile implants for impotence hormonal therapy for impotence

What about penile injection therapy for erectile dysfunction?

Penile injection therapy is non surgical technique used to treat impotence. The man injects medication (usually alprostadil) into the base of his penis. This causes the penis to become hard almost immediately. The erection then lasts for up to one to two hours. Use of the injections is limited to not more than once a day and three times a week. Several clinic visits are usually needed to establish the dose of medication required. Treatment is available on the NHS.

Penile injections have the advantage of not involving surgery. They are also effective in many dialysis patients. It is not known, however, whether the success rate for these injections in kidney patients is as high as 70%.


Injection therapy can be an alternative for the 30-40% of men who commonly fail with Viagra. The best treatment for erectile dysfunction, however, depends on many things. These include a man's health and personal and physical tolerance for the treatment. A man with erectile dysfunction should involve his spouse or partner and his doctor in the treatment decision.

There are several drugs which can be injected directly into the erectile tissues of the penis to cause an erection. The most commonly used are papaverine (Papaverine hydrochloride), phentolamine (Regitine), and prostaglandin E1 (Caverject, Prostin, or Alpoprostadil), which can be taken singularly or in combination. Erection usually begins within 15 minutes and may last several hours.

Penile injection therapy involves injecting a single drug or a combination of drugs into the side of the penis. This produces a hard erection that can last for one to two hours. These drugs must be used exactly as prescribed by the physician. If not used correctly, the result could be a prolonged erection, called priapism. When priapism occurs, the blood fails to drain from the penis. This can damage the penile tissue and be extremely painful. A person who has a history of substance abuse, therefore, would be a risky candidate for this therapy since its success requires the exact use of the prescribed drug. Penile injections would be a difficult option for an individual with SCI
with limited hand function to use on his own. He must have a partner who is willing to learn to give the injections.

Some men must combine the injection with an external vacuum device to get satisfactory results. This procedure, however, can be cumbersome and expensive. The additional time it takes tends to reduce romantic spontaneity.

Caverject is the trade name for an injectable solution of prostaglandin E1 (PGE1) or alprostadil, which is manufactured by Pharmacia-Upjohn. There are other variants of this including Edex, a similar product from Schwarz-Pharma. Caverject makes the shot kit. It is portable and does not require refrigeration until you mix the ingredients. It's expensive, compared to the PGE1 or PPP (Prostaglandin, Papaverine and Phentolamine). A popular complaint is that the needle is very large. Many here will tell you to purchase the small needles that diabetics use for insulin injections. Mix your powder and liquid using the large needle supplied with the kit, then change to the small needle for the injection. The reason the company supplies large needles may be the worry you might break off the needle in your dick and sue them.

Bimix and Trimix are injectables for intracavernosal administration. They refer to any combination of either two or three chemicals. Bimix is often a mixture of papaverine and phentolamine, while Trimix (PPP) would add PGE1. Other cocktails are used, mainly in Europe. These mixtures are not commercially available but must be mixed by a compounding pharmacy. They are generally much cheaper than Caverject or Edex, and tend to minimize aching in the penis or testicles which is a problem in some men with Prostaglandin (PGE-1) alone. A compounding pharmacy is one which will create custom medications on a doctor's prescription; it usually doesn't include the corner drugstore or large chain pharmacies.

More information on impotence (erectile dysfunction)

What is impotence or erectile dysfunction? - Impotence is the inability of the male to have an erection. Some men may become impotent after having diabetes for a long time because the nerves or blood vessels have become damaged. Impotence may have a physiological or psychological basis.
How does erection occur? - Erection begins with sensory and mental stimulation. Impulses from the brain and local nerves cause the muscles of the corpora cavernosa to relax, allowing blood to flow in and fill the open spaces.
What causes impotence? - A common cause of impotence is a high level of atherosclerosis in the arteries feeding the penis. Damage to arteries, smooth muscles, and fibrous tissues, often as a result of disease, is the most common cause of impotence.
What are the physical causes of impotence? - Physical impotence occurs when there is a problem with any of the systems needed to get or maintain an erection. Hardening of the arteries can affect the artery leading to the penis so that it cannot dilate enough to deliver all the blood necessary for an erection.
What are the psychological causes of impotence? - Psychological causes of impotence often include work pressures, financial worries, fear of aging, or frustration with relationships. Depression and anxiety disorders are cited as the most common causes of psychological impotence.
How is impotence (erectile dysfunction) treated? - Treatment depends on the cause. Testosterone supplements may be used for cases with hormonal deficiency. Drugs for treating impotence can be taken orally or injected directly into the penis.
What're non-prescription treatments for impotence? - Among the herbs used for erectile dysfunction are yohimbine, gingko biloba (to increase blood flow), ginseng, pygeum, and muira puama. A penile sheath is a rigid or semi-rigid support put over the penis to support it for intercourse.
What is MUSE? - MUSE is short for "medicated urethral system for erection." This treatment is based on the discovery that the urethra can absorb certain medications, which can then pass into the surrounding erectile tissue creating an erection.
What is Viagra (sildenafil citrate)? - Viagra (sildenafil citrate), a prescription medication for the treatment of erectile dysfunction, is the first pill available that's been proven to improve erections in most men with impotence.
What is Levitra (vardenafil)? - Levitra (vardenafil HCl) is a PDE inhibitor drug. This medication helps improve erection during sexual arousal and activity but erection should end after sexual activity is complete.
What is Cialis (tadalafil)? - Tadalafil (Cialis?) is a drug used to treat male erectile dysfunction (impotence). The generic name for this compound is tadalafil.
What about penile injection therapy? - Penile injection therapy is non surgical technique used to treat impotence. Penile injections have the advantage of not involving surgery. They are also effective in many dialysis patients.
What are penile implants for impotence? - Penile implants (often called "internal penile pumps") are one of several erectile dysfunction treatment options. The inflatable penile prosthesis is a pump system surgically placed in the penis.
What is hormonal therapy for impotence? - Sexual desire (libido) and an overall sense of well-being are likely to improve when serum testosterone levels (the level of the male hormone in the blood) are restored.
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